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Browsing by Author "Costa, Miguel"

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  • Acute Campylobacter spp. gastroenteritis in the Pediatric Emergency Department of a level II hospital
    Publication . Sá, Liliana; Pinheiro, Teresa; Silva, Joana; Pedrosa, Adriana; Soares, Laura; Costa, Miguel; Rocha, Cristina
    Introduction: Campylobacter spp. is the main cause of pediatric acute bacterial gastroenteritis (ABG) in the European Union, with greater incidence in children under five years old. Most patients present complete recovery within days of infection, with no associated comorbidities. Antibiotic therapy should be reserved for severe cases. Objectives: The aim of this study was to investigate the epidemiology, symptoms, treatment, and complications of Campylobacter spp. infection in pediatric patients with ABG. Material and methods: Case-by-case review of the clinical records of patients evaluated in the Pediatric Emergency Department of a level II hospital with a diagnosis of ABG and Campylobacter spp. isolated from stool samples over a five-year period (2013-2017). Results: Of the 1990 stool tests performed, 637 (32%) were positive for the presence of bacteria. Campylobacter spp. was identified in the samples of 459 patients (72%). Eighteen patients were excluded for insufficient data, making up a final sample of 441 patients, with a mean age of three years old. Clinically, patients presented with aqueous diarrhea (59.6%), bloody diarrhea (43.8%), bloody and mucus diarrhea (15.4%), mucus diarrhea (3.9%), vomiting (36.3%), abdominal pain (24.3%), fever (63%), seizures (0.9%), and rash (0.2%). Eighty-nine patients were hospitalized. Eleven patients received antibiotic therapy. Discussion: This study represents the largest national case-by-case review of ABG by Campylobacter spp. in the pediatric population. Campylobacter was the main bacteria identified, mostly associated with self-limited disease. Conclusion: A judicious use of stool tests allows etiological identification in ABG. The growing number of cases of ABG by Campylobacter spp. reinforces the need for better hygiene procedures.
    2022-03Journal article Open access Show more
  • Biochemical clinical case
    Publication . Silva, Joana Vanessa; Ferreira, Joana; Silva, Mariana; Costa, Miguel
    Bisalbuminemia is a qualitative albumin variation defined by coexistence of two types of serum albumin with different electrophoretic mobilities in the same individual. It can be of two different types: hereditary (or permanent) and acquired (or transient). Herein is described a rare case of hereditary bisalbuminemia in a healthy infant, incidentally found during elevated aminotransferase study. Despite not having pathological significance, acknowledgement of this analytical alteration is key for adequate management of these patients.
    2021-12Journal article Open access Show more
  • Childhood neglect: Another perspective on childhood obesity
    Azevedo, Inês Alexandra; Aguiar, Benedita Bianchi; Silva, Joana; Marques, Elizabeth; Silva, Maria José; Monteiro, Virgínia; Gomes, Lúcia; Costa, Miguel
    Childhood obesity is a multifactorial condition. Extreme cases are often associated with the inability of caregivers to follow the recommended diet plan, despite prior warnings of the potential risks associated of non-compliance.A seven-year-old girl with a body mass index (BMI) of 38.6 kg/m2 (z-score +7.3) and multiple comorbidities was seen in a Pediatric Nutrition outpatient consultation. After several attempts to educate her guardians about the potential risks of obesity, the girl was referred for a multidisciplinary evaluation and placed in a children’s home. With adequate nutrition and regular exercise, significant improvements were achieved in BMI (23.5 kg/m2; z-score +2.06). After three years, the girl was returned to her family home by court order, with subsequent worsening of her BMI (maximum 40.7 kg/m2; z-score +4.07), despite information provided by the medical team to social services and the court. Given that caregivers play an essential role in the prevention of childhood obesity, persistent refusal to follow therapeutic recommendations coupled with indifference in the face of red flags meets the criteria for abuse.
    2023-12-31Text Open access Show more