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Management of von Willebrand disease type 3 during pregnancy - 2 cases reports.
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Orientador(es)
Resumo(s)
BACKGROUND:
von Willebrand disease type 3, is an extremely rare condition. It can be severe and potentially life-threatening, particularly in pregnant women during labor and subsequently during early puerperium. Due to its rarity, there is no optimal treatment/management during pregnancy.
CASE:
We describe two cases of pregnant women with von Willebrand disease type 3, and its successful surveillance and treatment with Haemate P FVIII (human plasma-derived von Willebrand Factor-ristocetin co-factor associated with human coagulation factor VIII), during pregnancy, partum and puerperium.
CONCLUSIONS:
Daily prophylaxis with Haemate P FVIII in women with von Willebrand disease type 3, starting 2 hours before caesarean section until the 7th day of puerperium, associated with close analytical and clinical surveillance seems to be a safe clinical option.
Descrição
Palavras-chave
von Willebrand disease Type 3 Pregnancy Management
Contexto Educativo
Citação
Eur Rev Med Pharmacol Sci. 2013 Nov;17(21):2857-9.
Editora
Verduci