Publication
Cross-allergy between penicillins and cephalosporins: a paradigm shift
| dc.contributor.author | Dias, Liliana | |
| dc.contributor.author | Neves, Claudia | |
| dc.date.accessioned | 2023-02-02T10:38:46Z | |
| dc.date.available | 2023-02-02T10:38:46Z | |
| dc.date.issued | 2022-03 | |
| dc.description.abstract | Allergic reactions to beta-lactam antibiotics are the most common cause of allergic drug reactions. The incorrect diagnosis prevents patients from receiving a highly effective therapy. The potential cross-reactivity between penicillin and cephalosporin has very significant therapeutic implications. Penicillins and cephalosporins share a common beta-lactam ring and side chains. A number of studies indicate that the R1 side chain, rather than the ring itself, is the determining factor for cross-reactivity. Herein is presented a review of the immunologic mechanisms implicated in penicillin and cephalosporin cross-reactivity and a practical approach to the use of cephalosporins in patients allergic to penicillin. | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.citation | Nascer e Crescer - Birth and Growth Medical Journal 2022;31(1):31-37. doi:10.25753/BirthGrowthMJ.v31.i1.20898 | pt_PT |
| dc.identifier.doi | https://doi.org/10.25753/BirthGrowthMJ.v31.i1.21607 | pt_PT |
| dc.identifier.eissn | 2183-9417 | |
| dc.identifier.uri | http://hdl.handle.net/10400.16/2761 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.publisher | Centro Hospitalar Universitário do Porto | pt_PT |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc/4.0/ | pt_PT |
| dc.subject | cephalosporin | pt_PT |
| dc.subject | cross-reactivity | pt_PT |
| dc.subject | penicillin | pt_PT |
| dc.subject | side chain | pt_PT |
| dc.title | Cross-allergy between penicillins and cephalosporins: a paradigm shift | pt_PT |
| dc.title.alternative | Reatividade cruzada entre penicilinas e cefalosporinas: mudança de paradigma | pt_PT |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.conferencePlace | Porto | pt_PT |
| oaire.citation.endPage | 37 | pt_PT |
| oaire.citation.issue | 1 | pt_PT |
| oaire.citation.startPage | 31 | pt_PT |
| oaire.citation.title | Nascer e Crescer - Birth and Growth Medical Journal | pt_PT |
| oaire.citation.volume | 31 | pt_PT |
| person.familyName | Rodrigues Dias | |
| person.familyName | Pedrosa Neves | |
| person.givenName | Liliana | |
| person.givenName | Claudia Margarida | |
| person.identifier.ciencia-id | 6418-41B9-C723 | |
| person.identifier.ciencia-id | 8C1D-5B5C-BBF8 | |
| person.identifier.orcid | 0000-0001-7032-5212 | |
| person.identifier.orcid | 0000-0003-1201-5720 | |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | article | pt_PT |
| relation.isAuthorOfPublication | 4f2ef1d4-4016-4c90-87c9-5bac2697c9f9 | |
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