Publication
The successful treatment with ixekizumab in a multi-failure psoriasis patient
| dc.contributor.author | Azevedo, A. | |
| dc.contributor.author | Torres, T. | |
| dc.date.accessioned | 2019-07-18T15:42:46Z | |
| dc.date.available | 2019-07-18T15:42:46Z | |
| dc.date.issued | 2018-09-10 | |
| dc.description.abstract | We report a patient with severe psoriasis who failed to respond to phototherapy, conventional systemic treatment and four biologic agents (etanercept, ustekinumab, adalimumab and secukinumab). Combination of a higher-dose secukinumab regimen with phototherapy had no success. Remarkably, ixekizumab, an IL-17A inhibitor, provided almost complete psoriasis clearance after 24 weeks of treatment. The reason for the success of ixekizumab after the failure to respond to a biologic with same mechanism of action is still unknown. Interestingly, failure of secukinumab does not preclude future therapeutic success with a second IL-17A-inhibitor. | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.citation | Dermatol Online J. 2018 Sep 10;24(9). pii: 13030/qt2qn1p4bz | pt_PT |
| dc.identifier.issn | 1087-2108 | |
| dc.identifier.uri | http://hdl.handle.net/10400.16/2280 | |
| dc.language.iso | por | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.publisher | University of California Davis | pt_PT |
| dc.relation.publisherversion | https://escholarship.org/uc/item/2qn1p4bz | pt_PT |
| dc.title | The successful treatment with ixekizumab in a multi-failure psoriasis patient | pt_PT |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.conferencePlace | United States of America | pt_PT |
| oaire.citation.issue | 9 | pt_PT |
| oaire.citation.startPage | pii: 13030/qt2qn1p4bz | pt_PT |
| oaire.citation.title | Dermatology Online Journal | pt_PT |
| oaire.citation.volume | 24 | pt_PT |
| person.familyName | Torres | |
| person.givenName | Tiago | |
| person.identifier | 1077508 | |
| person.identifier.ciencia-id | FF1B-8834-7AE0 | |
| person.identifier.orcid | 0000-0003-0404-0870 | |
| person.identifier.rid | C-2604-2014 | |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | article | pt_PT |
| relation.isAuthorOfPublication | 99c82895-36fa-49af-927a-f75fa1f9bd56 | |
| relation.isAuthorOfPublication.latestForDiscovery | 99c82895-36fa-49af-927a-f75fa1f9bd56 |