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Clinical phenotypes of Cerebral Amyloid Angiopathy
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J Neurol Sci. 2007 Jun 15;257(1-2):23-30. Epub 2007 Mar 6.
Clinical phenotypes of Cerebral Amyloid Angiopathy.
Maia LF, Mackenzie IR, Feldman HH.
Source
Department of Neurology, Hospital Geral Santo António, Porto, Portugal.
Abstract
The term Cerebral Amyloid Angiopathy (CAA) is used to describe the pathological changes occurring in cerebral blood vessels, both leptomeningeal and cortical that result from the deposition of amyloid proteins. This CNS vasculopathy is associated with a spectrum of clinical phenotypes that include both ischemic and hemorrhagic presentations. Dementia, cognitive impairment and transient neurological symptoms or signs are also being increasingly recognized as part of the CAA clinical spectrum. This review covers the clinical, pathological and neuroimaging aspects of CAA.
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Citação
J Neurol Sci. 2007 Jun 15;257(1-2):23-30. Epub 2007 Mar 6.