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Pollen-food syndrome during pediatric age: a case series

datacite.subject.fosCiências Médicas
dc.contributor.authorCunha, Francisca
dc.contributor.authorRodrigues dos Santos, Filipa
dc.contributor.authorCunha, Leonor
dc.contributor.authorFalcão, Helena
dc.date.accessioned2025-10-22T13:50:16Z
dc.date.available2025-10-22T13:50:16Z
dc.date.issued2025-06-30
dc.description.abstractIntroduction: Pollen-food syndrome (PFS) is an immunoglobulin E-mediated reaction, caused by cross-reactivity between pollen and antigens of foods such as those in fruits, vegetables, and/or nuts, in patients with pollinosis. Aims and Methods: The aim of this study was to present clinical manifestations of PFS, using a case series of six pediatric patients with PFS and pollen allergy referred to our Allergy and Clinical Immunology Department. Results: The age at diagnosis ranged between 10 and 17 years old, and three of the patients were male. All patients reported experiencing oral allergy syndrome. The main foods reported as triggers were apple, peach, pear, kiwi and banana. The allergic diagnostic workup revealed sensitisation to PR-10 and profilins, the main proteins involved in PFS. Currently, all patients remain asymptomatic after the fresh fruits’ eviction. Conclusion: We emphasize the importance of recognition of this entity to provide an adequate management.por
dc.identifier.citationNascer e Crescer - Birth and Growth Medical Journal 2025;34(2):83-86. doi:10.25753/BirthGrowthMJ.v34.i2.35602
dc.identifier.doi10.25753/BirthGrowthMJ.v34.i2.35602
dc.identifier.issn2183-9417
dc.identifier.urihttp://hdl.handle.net/10400.16/3717
dc.language.isoeng
dc.publisherUnidade Local de Saúde de Santo António
dc.relation.hasversionhttps://revistas.rcaap.pt/bgmj/article/view/35602
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/
dc.subjectcross-reactivity
dc.subjectfood allergy
dc.subjectpediatric age
dc.subjectpollen-food syndrome
dc.titlePollen-food syndrome during pediatric age: a case seriespor
dc.title.alternativeSíndrome Pólen-frutos em idade pediátrica: uma série de casos 1. Department of Allergy and Clinical Immunology, Unidade Local de Saúde de Coimbra. 3004-561 Coimbra, Portugal. francisca.cunha.tavares@gmail.com 2. Department of Allergy and Clinical Immunology, Unidade Local de Saúde de Santo António. 4099-011 Porto, Portugal. filipair.santos@gmail.com; leonorcunhagraca@sapo.pt; falcao.helena@gmail.comABSTRACTIntroduction: Pollen-food syndrome (PFS) is an immunoglobulin E-mediated reaction, caused by cross-reactivity between pollen and antigens of foods such as those in fruits, vegetables, and/or nuts, in patients with pollinosis. Aims and Methods: The aim of this study was to present clinical manifestations of PFS, using a case series of six pediatric patients with PFS and pollen allergy referred to our Allergy and Clinical Immunology Department. Results: The age at diagnosis ranged between 10 and 17 years old, and three of the patients were male. All patients reported experiencing oral allergy syndrome. The main foods reported as triggers were apple, peach, pear, kiwi and banana. The allergic diagnostic workup revealed sensitisation to PR-10 and profilins, the main proteins involved in PFS. Currently, all patients remain asymptomatic after the fresh fruits’ eviction. Conclusion: We emphasize the importance of recognition of this entity to provide an adequate management.Keywords: cross-reactivity; food allergy; pediatric age; pollen-food syndromeRESUMOIntrodução: A síndrome pólen-alimento (SPF) é uma reação IgE mediada, causada pela reatividade cruzada entre o pólen e antigénios alimentares (frutos e vegetais crus) em doentes com polinose. Objetivos e métodos: O objetivo deste estudo foi apresentar as manifestações clínicas da SPF, ao analisar seis doentes pediátricos com diagnóstico de polinose e SPF, referenciados ao Departamento de Imunoalergologia. Resultados: A idade ao diagnóstico variou entre os 10 e os 17 anos e três dos doentes eram do sexo masculino. Todos os doentes referiram síndrome de alergia oral. Os principais alimentos desencadeantes foram a maçã, o pêssego, a pera, o kiwi e a banana. A investigação diagnóstica alérgica revelou sensibilização ao PR-10 e às profilinas, as principais proteínas envolvidas na SPF. Atualmente, todos os doentes permanecem assintomáticos após a evicção dos frutos frescos.Palavras-chave: alergia alimentar; idade pediátrica; reatividade cruzada; síndrome pólen-frutospor
dc.typetext
oaire.citation.endPage86
oaire.citation.issue2
oaire.citation.startPage83
oaire.citation.titleNascer e Crescer - Birth and Growth Medical Journal
oaire.citation.volume34
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85

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