Alba, DianaPimenta, SofiaMachado, ÂngelaFerreira, Jorge Abreu2025-11-042025-11-042024-06-30Nascer e Crescer - Birth and Growth Medical Journal 2024;33(2):144-146. doi:10.25753/BirthGrowthMJ.v33.i2.275932183-9417http://hdl.handle.net/10400.16/3790Urticaria multiforme (UM) is an allergic hypersensitivity reaction characterized by the acute onset of polycyclic and annular wheals with ecchymotic centers. It is more common in children under 4 years of age, who typically present with a pruritic rash and nontoxic appearance. The diagnosis is clinical. The condition usually has a favorable response to antihistamines and self-limited course. UM is probably underdiagnosed as it is often confused with erythema multiforme and serum sickness-like reaction. Herein is reported a case of UM in a four-year-old boy, followed by a review of the literature on the subject.engdermatologyerythema multiformepruritusrashurticaria multiformetext10.25753/BirthGrowthMJ.v33.i2.27593