Santos, RaquelQuintela, CarolinaSilva, Joana AzevedoPeralta, LígiaSá, Aida2025-10-222025-10-222025-06-30Nascer e Crescer - Birth and Growth Medical Journal 2025;34(2):87-89. doi:10.25753/BirthGrowthMJ.v34.i2.387192183-9417http://hdl.handle.net/10400.16/3718Phytophotodermatosis (PPD) is a skin reaction caused by contact with furocoumarins, photosensitizing substances present in certain plants, followed by exposure to ultraviolet radiation. Herein we report a case of a 17-year-old teenager who developed a cutaneous reaction after using rue (Ruta graveolens) as a homemade treatment for acne. The condition presented with a characteristic inflammatory phase, followed by a hyperpigmentation phase. A diagnosis of PPD due to rue was established, and with rue eviction there was a full resolution. The authors aim to raise awareness about this condition which requires a high level of clinical suspicion for identifying the etiological agent. Prompt recognition and intervention are crucial in preventing the worsening and recurrence of the reaction.engcontact dermatitisphytophotodermatosisruetext10.25753/BirthGrowthMJ.v34.i2.38719