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- Severe symptomatic hyperparathyroidism—Is it carcinoma?—Case report and literature reviewPublication . A. Pereira, Catarina; Garrido, Susana; Amaral, Cláudia; Lima, Olinda; Cardoso, HelenaParathyroid carcinoma is a rare disease, difficult to diagnose and associated with a poor prognosis. It must be suspected preoperatively, based on clinical and imaging grounds, in order to perform the best surgical option and avoid compromising patient's prognosis.